BEGIN:VCALENDAR VERSION:2.0 PRODID:-//132.216.98.100//NONSGML kigkonsult.se iCalcreator 2.20.4// BEGIN:VEVENT UID:20250928T212122EDT-1254Ts1A7u@132.216.98.100 DTSTAMP:20250929T012122Z DESCRIPTION:Dr. Jackie Vogel\n 91Ö±²¥ - Quantitative Life Science s\n\n \n\nNanoscale analysis of spindle formation in living cells\n\nAll c ells must duplicate and partition their chromosomes during cell division. In eukaryotic cells\, the mitotic spindle\, a complex biological machine c omposed of microtubules and their associated proteins\, ensures chromosome s are accurately partitioned into daughter cells. The formation of the mit otic spindle involves the formation of microtubules\, and the control of b oth microtubule number and their interactions. The initial state of this s ystem is poorly understood\, as are the events that control the number of microtubules and how they interact to form the highly ordered and stereoty ped spindles that efficiently segregate the chromosomes. In my talk\, I wi ll describe our efforts determine how the spindle is formed\, and how the number and interactions of microtubules are controlled as the spindle asse mbles. In particular\, I will describe how phosphorylation of intrinsicall y disordered regions of g-tubulin\, the protein that nucleates the formati on of microtubules\, determines the number of microtubules and how they in teract with force generating proteins.\n\n \n\n \n DTSTART:20200115T163000Z DTEND:20200115T173000Z LOCATION:Room 1/12\, Strathcona Anatomy and Dentistry Building\, CA\, QC\, Montreal\, H3A 0C7\, 3640 rue University SUMMARY:Departmental Seminar: Dr. Jackie Vogel URL:/anatomy/channels/event/departmental-seminar-dr-ja ckie-vogel-301376 END:VEVENT END:VCALENDAR