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In this 4-hour workshop, participants will be introduced to the fundamentals of high-throughput proteomics and protein analysis. Attendees will learn about high-throughput proteomic methodologies, data production, and formats. Combining structured modules and practical exercises, participants will learn how to apply theoretical concepts, conduct association studies with proteomics, and find genetic associations with protein levels.听
By the end of this workshop, participants will be able to:
1. Differentiate between the two popular high throughput proteomic technologies (SomaLogic and OLink) and understand the differences between the two platforms.
2. Revise basic linear regression, an introduction to other types of models such as GAMs and LMMs, and will learn how to decide whether a model is appropriate.
3. Conduct hands-on quality control, generate some models to adequately reflect proteomic information, and derive basic analyses from the information.
4. Conduct protein GWAS and cis vs. trans pQTL analysis.听听
Pre-requisites:
1. Basic understanding of R (the Intro to R by MiCM is sufficient) - with RStudio already installed.
2. A computer with a minimum of 2GB free disk space, running a current version of Windows, Mac OS X, or Linux.
3. Necessary packages installed.

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**IMPORTANT NOTICE: Attendance for 91直播 graduate students and postdoctoral fellows is subsidized by Graduate and Postdoctoral Studies. All other attendees such as undergraduate students, interns and/or graduate students from other institutions are required to purchase a ticket to cover organizational and staffing costs. To complete your registration, you must e-transfer $10 (undergraduate student/trainee) $25 (staff) or $100 (faculty) to workshop-micm [at] mcgill.ca within 24 hours of RSVP'ing to this event. If we do not receive your e-transfer, you will have given up your spot.