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UID:20250929T222654EDT-5364SIjAvl@132.216.98.100
DTSTAMP:20250930T022654Z
DESCRIPTION:Meroterpenoid natural products are important bioactive molecule
 s with broad distribution throughout nature. In Streptomyces bacteria\, na
 phthoquinone-based meroterpenoids comprise a simple yet structurally fasci
 nating group of natural product antibiotics that are enzymatically constru
 cted via a series of asymmetric alkene and arene halofunctionalization rea
 ctions. This lecture will discuss our discovery and characterization of a 
 group of vanadium-dependent chloroperoxidase enzymes that catalyze halogen
 -assisted cyclization and rearrangement reactions and have inspired biomim
 etic syntheses of numerous meroterpenoid natural products\, including the 
 napyradiomycins and merochlorins.\n
DTSTART:20171121T180000Z
DTEND:20171121T193000Z
LOCATION:Rm 10\, Maass Chemistry Building\, CA\, QC\, Montreal\, H3A 0B8\, 
 801 rue Sherbrooke Ouest
SUMMARY:Chemical Society Seminar: Dr. Bradley Moore - Asymmetric Alkene and
  Arene Halofunctionalization Reactions in Meroterpenoid Biosynthesis
URL:/chemistry/channels/event/chemical-society-seminar
 -dr-bradley-moore-asymmetric-alkene-and-arene-halofunctionalization-282859
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