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UID:20250929T125824EDT-1324GvGkxE@132.216.98.100
DTSTAMP:20250929T165824Z
DESCRIPTION:Abstract:\n\nConjugated polymers and oligomers are typically th
 ought of being relevant within the context of emerging optoelectronic tech
 nologies. This presentation will highlight how a subset of these materials
 \, namely conjugated oligoelectrolytes (COEs) can be designed for the pert
 urbation and modulation of microbial processes. The first section of the t
 alk will focus on the self-assembly and intercalation of COEs with lipid b
 ilayer membranes. In the case of microbial systems\, one finds that it is 
 possible to modulate important membrane properties. A continuum of effects
  is achievable that directly relates to the molecular connectivity of the 
 COE. One can increase or decrease permeability by tuning the number of the
  repeat units in the conjugated backbone. These features translate to appl
 ications in biocatalysis and biofuel production that is challenged by the 
 environmental stress provided by the product of the reaction. Redox functi
 onalities can also be incorporated within the COE framework that allow one
  to tune the potential for electron injection or extraction in electrogeni
 c bacteria. Most recently\, we have discovered that certain select COEs ar
 e highly efficacious antibiotics with minimal toxic side effects to mammal
 ian cells. Indeed\, some of these COEs are capable of curing mice infected
  with multidrug resistant (MDR) infections that could not be treated with 
 the current arsenal of antibiotics. We are encouraged to continue focusing
  our attention on these developments given that the anticipated rise of un
 treatable infections by MDR bacteria is one of the most important current 
 threats to public health.\n\nBio:\n\nProfessor Guillermo (Gui) Bazan recei
 ved his B.Sc. (summa cum laude) from the University of Ottawa. His Ph.D. s
 tudies were carried out at the Massachusetts Institute of Technology under
  the guidance of Nobel Laurate Richard R. Schrock. He was a postdoctoral a
 ssociate at the California Institute of Technology with Professor John E. 
 Bercaw.\n\nProfessor Bazan began his independent academic career at the Un
 iversity of Rochester in 1992. He was recruited by the University of Calif
 ornia\, Santa Barbara in 1998\, and currently holds appointments in the De
 partments of Materials and in Chemistry & Biochemistry. Relevant awards an
 d recognitions include: Thomson Reuter “Most Influential Scientific Minds”
 \, 2015\; Fellow of the Royal Society of Chemistry\, 2014\; Top 50 Materia
 l Scientists by Citation and Impact\, Thompson Reuters\, 2011\; Macromolec
 ules Advisory Board\, 2009\; Professor of the Chang Jiang Scholars Profess
 or\, 2009\; Advanced Materials Editorial Advisory Board\, 2008\; Fellow of
  the American Association for the Advancement of Science\, 2007\; American
  Chemical Society Cope Scholar Award\, 2006\; Bessel Award\, Humboldt Foun
 dation\, 2005\; NSF Special Creativity Award\, 2003\; Union Carbide Innova
 tion Award\, 1999\; Union Carbide Innovation Award\, 1998\; Closs Lecturer
 \, University of Chicago\, 1997\; Camille and Henry Dreyfus Teacher-Schola
 r Award\, 1996-1998\; Sloan Research Fellow Award\, 1996-1998\; NSF CAREER
  Award\, 1995-1998\; Dreyfus New Faculty Award\, 1992-1993\; NSERCC Postdo
 ctoral Fellowship\, November 1990-May 1992 and the NSERCC 1967 Science and
  Engineering Scholarship\, September 1986-June 1990.\n\nThree spin-off com
 panies are associated with his laboratories and the sudents in his group. 
 They include Sirigen (purchased by Becton Dickinson)\, NEXT Energy\, and A
 peel Technologies. Prof. Bazan holds approximately thirty patents. Thirty 
 of his previous students and postdoctoral associates now lead successful a
 cademic positions.\n\n \n
DTSTART:20190312T170000Z
DTEND:20190312T183000Z
LOCATION:Room 10\, Maass Chemistry Building\, CA\, QC\, Montreal\, H3A 0B8\
 , 801 rue Sherbrooke Ouest
SUMMARY:Chemical Society Seminar: Guillermo Bazan - Molecular Design of Con
 jugated Oligoelectrolytes for Bioelectrochemical Applications and Antibiot
 ic Development
URL:/chemistry/channels/event/chemical-society-seminar
 -guillermo-bazan-molecular-design-conjugated-oligoelectrolytes-292500
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