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DESCRIPTION:Register here.\n\nStream via vimeo here.\n\n\nAna Luisa Pinho\n
 \nBrainsCAN Postdoctoral Fellow\, Western University\, Canada\n\nAbstract:
  Functional Magnetic Resonance Imaging (fMRI) provides means to characteri
 ze brain activations in response to behavior. However\, cognitive neurosci
 ence has been limited to group-level effects referring to the performance 
 of specific tasks. To obtain the functional profile of elementary cognitiv
 e mechanisms\, the combination of brain responses to many tasks is require
 d\, by pooling data or results from different single-task studies. Meta-an
 alyses allow the accumulation of knowledge across studies. Yet\, they are 
 typically impacted not only by inter-subject and inter-site variability bu
 t also loss of information from sparse peak-coordinate representations. In
  this talk\, I will address a battery of studies\, which combine deep phen
 otyping and multitask-fMRI approaches to extensively investigate the funct
 ional signatures of the different components that characterize the human b
 ehavior. First\, I will describe a set of experiments\, based on temporall
 y controlled task designs\, reported in [1]\, [2] and [3]\, in which we le
 verage a collection of source task-fMRI data from the Individual Brain Cha
 rting (IBC) dataset. The main goal herein is to investigate the feasibilit
 y of performing individual functional brain atlasing\, free from inter-sub
 ject and inter-site variability\, as an effort to establish an univocal re
 lationship between functional segregation of brain regions and elementary 
 mental functions. Results show that individual topographies---common to al
 l tasks---are consistently mapped within and\, to a lesser extent\, across
  participants. Besides\, prediction scores associated with the reconstruct
 ion of contrasts of one task from the remaining ones reveal the quantitati
 ve contribution of each task to these common representations. Yet\, scores
  decreased when subjects were permuted between train and test\, confirming
  that topographies are driven by subject-specific variability. In addition
 \, we demonstrate how cognitive mapping can benefit from contrasts accumul
 ation\, by analyzing the functional fingerprints of a set of individualize
 d regions-of-interest from the language network. Second\, I will describe 
 our ongoing work on the quality-assessment and validation of a subset of t
 asks from the IBC dataset based on naturalistic stimuli using two types of
  encoding models: the unsupervised Fast Shared Response Model [4]\, and a 
 feature-defined model based on Deep Convolutional Neural Networks [5\, 6].
  \n\nBio: Ana Luísa Pinho graduated in Engineering Physics at Instituto Su
 perior Técnico (University of Lisbon\, Lisbon\, Portugal). During her doct
 oral studies at Karolinska Institutet (Stockholm\, Sweden)\, she studied t
 he neurocognitive mechanisms implicated in musical creativity through fMRI
 . Afterwards\, she worked as a Postdoctoral Researcher at NeuroSpin (Paris
 \, France) on dataset development and brain atlasing using neuroimaging da
 ta\; she was directly involved in the Individual Brain Charting project\, 
 a collaborative ten-years consortium under the Human Brain Project flagshi
 p. She is now a BrainsCAN Postdoctoral Fellow at Western University (Londo
 n ON\, Canada) working on the characterization of the cortico-basal gangli
 a-cerebellar circuitry involved in the ability to form temporal prediction
 s during rhythmic and non-rhythmic sequences of events. To this end\, she 
 is leveraging a cognitive-specific battery of task-fMRI data and applying 
 atlasing techniques as means to identify functional specialization and con
 nectivity in this cortical-subcortical network.\n\n\nThe Feindel Brain and
  Mind Seminar Series will advance the vision of Dr. William Feindel (1918–
 2014)\, Former Director of the Neuro (1972–1984)\, to constantly bridge th
 e clinical and research realms. The talks will highlight the latest advanc
 es and discoveries in neuropsychology\, cognitive neuroscience\, and neuro
 imaging.\n\nSpeakers will include scientists from across The Neuro\, as we
 ll as colleagues and collaborators locally and from around the world. The 
 series is intended to provide a virtual forum for scientists and trainees 
 to continue to foster interdisciplinary exchanges on the mechanisms\, diag
 nosis and treatment of brain and cognitive disorders.\n\n \n
DTSTART:20230322T190000Z
DTEND:20230322T200000Z
LOCATION:Jeanne Timmins Amphitheatre\, Montreal Neurological Institute\, CA
 \, QC\, Montreal\, H3A 2B4\, 3801 rue University
SUMMARY:Feindel Brain and Mind Seminar Series: Deep behavioral phenotyping 
 in functional MRI for cognitive mapping of the human brain
URL:/neuro/channels/event/feindel-brain-and-mind-semin
 ar-series-deep-behavioral-phenotyping-functional-mri-cognitive-mapping-346
 381
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